NTD and TCS: Malformations of the Spinal Cord in Children and Adults

NTD and TCS: Malformations of the Spinal Cord in Children and Adults

One of the most common and life-threatening birth defects are known as neural tube defects (NTDs). These defects are categorized by an opening in the spinal cord or brain during development. Additionally, a less common spinal cord disorder also occurs in adults called adult tethered cord syndrome. This may go undiagnosed until adulthood when pain, sensory, and motor problems occur in a patient’s back.

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Gangliosides and Neurological Development

Gangliosides and Neurological Development

Recent developments in neuroscience have led to the discovery that glycolipid structures promote platelet activation and neuroinflammation, therefore having an imperative role neurological diseases such as Alzheimer’s Disease. Due to these recent developments new studies have shown that important developmental structures within the brain can also be a vital contributor towards finding preventative cures towards degenerative neural diseases.

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Brain - Gut Microbiota Connection

Brain - Gut Microbiota Connection

The process of learning about the human biology generally tends to systematize and separate the body into discrete units and understand their function as disparate parts. This often translates into the clinical world of diagnoses and treatments where diseases are isolated to their corresponding systems—Parkinson’s disease is viewed under a neurodegenerative lens, or patients with irritable bowel syndrome are sent to a gastroenterologist.

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Controlling the Brain with Optogenetics

Controlling the Brain with Optogenetics

Imagine controlling neuronal activity with nothing but a miniature flashlight. Shine the light on a set of neurons and they fire up, sending action potentials across the brain and back. Turn the light off and they’re back to resting state. Though perhaps a bit of an exaggeration, this idea basically captures the essence of optogenetics, which in more scientific terms refers to the use of light responsive “opsin” proteins to produce genetically modified neurons. 

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